Ubiquitous Presence in Mammalian Cells of Enzymatic Activity Specifically Cleaving 8‐Hydroxyguanine‐containing DNA

Here we report the finding of enzymatic activity that specifically cleaves DNA containing 8‐hydroxyguanine (oh(8)Gua) residues in various mammalian cells. To detect this activity, we used a synthetic double‐stranded DNA containing a single oh(8)Gua at a defined position as the substrate, and analyze...

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Detalles Bibliográficos
Autores principales: Yamamoto, Fuyumi, Kasai, Hiroshi, Bessho, Tadayoshi, Chung, Myung‐Hee, Inoue, Hideo, Ohtsuka, Eiko, Hori, Tomokatsu, Nishimura, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918833/
https://www.ncbi.nlm.nih.gov/pubmed/1506269
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00114.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918833/
https://www.ncbi.nlm.nih.gov/pubmed/1506269
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00114.x

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