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Augmentation by Bispecific F(ab′)(2) Reactive with P‐Glycoprotein and CD3 of Cytotoxicity of Human Effector Cells on P‐Glycoprotein Positive Human Renal Cancer Cells
A bispecific F(ba′)(2) was constructed that was composed of two Fab fragments, one derived from anti‐CD3 monoclonal antibody (mAb) (OKT3) and the other from anti P‐glycoprotein mAb (MRK 16). This bispecific F(ab′)(2) enhanced the binding and cytotoxicity of human peripheral blood mononuclear cells (...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1992
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918834/ https://www.ncbi.nlm.nih.gov/pubmed/1354668 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00116.x |