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Mouse‐Human Chimeric Antibody MH171 against the Multidrug Transporter P‐Glycoprotein

We have developed a mouse‐human chimeric antibody MH171, in which the antigen‐recognizing variable regions of the mouse monoclonal antibody MRK17 are joined with the constant regions of human IgG1 antibodies. The MRK17 recognizes specifically the multidrug transporter P‐glycoprotein and inhibits the...

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Detalles Bibliográficos
Autores principales:	Ariyoshi, Keiko, Hamada, Hirofumi, Naito, Mikihiko, Heike, Yuji, Seimiya, Hiroyuki, Maezawa, Kayoko, Tsuruo, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918864/ https://www.ncbi.nlm.nih.gov/pubmed/1352281 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01958.x

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