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The Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Cisplatin at Its Mean Lethal Concentration

HeLa S‐3 cells were treated with (195m)Pt‐radiolabeled cis‐diamminedichloroplatinum(II) (CDDP) under various conditions, and the relationship between lethal effect and the number of Pt atoms binding to DNA, RNA and proteins was examined. The mean lethal concentrations for the cells treated with CDDP...

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Detalles Bibliográficos
Autores principales:	Akaboshi, Mitsuhiko, Kawai, Kenichi, Maki, Hirotoshi, Akuta, Keizo, Ujeno, Yowri, Miyahara, Tokiharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918865/ https://www.ncbi.nlm.nih.gov/pubmed/1618702 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01959.x

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