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Enhancement of Lysosomal Enzyme Activity by Recombinant Human Tumor Necrosis Factor and Its Role in Tumor Cell Killing in vitro

We investigated the effect of recombinant human tumor necrosis factor (TNF) on the lysosomal enzyme activity of various established cell lines in vitro. Incubation of 1 × 10(6)TNF‐sensitive mouse tumorigenic fibroblasts (L‐M cells) in the presence of TNF (100 U/ml) for 48 h increased the total (the...

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Detalles Bibliográficos
Autores principales:	Watanabe, Naoki, Yamauchi, Naofumi, Neda, Hiroshi, Maeda, Masahiro, Tsuji, Yasushi, Okamoto, Tetsuro, Akiyama, Shinichiro, Sasaki, Hiroyoshi, Tsuji, Naoki, Niitsu, Yoshiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918887/ https://www.ncbi.nlm.nih.gov/pubmed/1644666 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00137.x

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