Cargando…
T cell mediated immunity after combination therapy with intralesional PV-10 and blockade of the PD-1/PD-L1 pathway in a murine melanoma model
Intralesional (IL) injection of Rose Bengal (PV-10) induces regression of injected and uninjected lesions in several murine tumor models. In this study, we investigated the anti-tumor response of combining IL PV-10 with blockade of the PD-1 / PD-L1 pathway and the role of immune cell populations in...
Autores principales: | Liu, Hao, Weber, Amy, Morse, Jennifer, Kodumudi, Krithika, Scott, Ellen, Mullinax, John, Sarnaik, Amod A., Pilon-Thomas, Shari |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918896/ https://www.ncbi.nlm.nih.gov/pubmed/29694419 http://dx.doi.org/10.1371/journal.pone.0196033 |
Ejemplares similares
-
Efficacy of intralesional injection with PV-10 in combination with co-inhibitory blockade in a murine model of melanoma
por: Pilon-Thomas, Shari, et al.
Publicado: (2014) -
Intralesional Injection of Rose Bengal Induces a Systemic Tumor-Specific Immune Response in Murine Models of Melanoma and Breast Cancer
por: Toomey, Paul, et al.
Publicado: (2013) -
Intralesional Rose Bengal in melanoma elicits tumor immunity via HMGB1
por: Liu, Hao, et al.
Publicado: (2015) -
Immune Checkpoint Blockade to Improve Tumor Infiltrating Lymphocytes for Adoptive Cell Therapy
por: Kodumudi, Krithika N., et al.
Publicado: (2016) -
Intralesional rose bengal in melanoma elicits tumor immunity via activation of dendritic cells by the release of high mobility group box 1
por: Liu, Hao, et al.
Publicado: (2016)