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Myeloprotective Activity of Deoxyspergualin: Influence on Splenic Colony‐forming Cell Injury and Antitumor Activity of Mitomycin C in Mice

We have examined the efficacy of deoxyspergualin (DSG) in protecting splenic colony‐forming cells (CFU‐S) from mitomycin C (MMC)‐induced damage. The main findings of the study are as follows. (1) When DSG was administered at doses of 1.5 and 3 mg/kg for 7 days before the MMC injection, the decrease...

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Detalles Bibliográficos
Autores principales: Nemoto, Kyuichi, Sugawara, Yumi, Ogino, Miwa, Mae, Takako, Abe, Fuminori, Takeuchi, Tomio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918928/
https://www.ncbi.nlm.nih.gov/pubmed/1517153
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01981.x