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Efficacy and Specificity of a Monoclonal Antibody‐Drug Conjugate in Chemotherapy by Intratumoral Injection

The murine monoclonal antibody (Mab) A7 conjugated to neocarzinostatin (A7‐NCS) was injected intratumorally (IT) into tumor bearing nude mice. Its pharmacokinetics and tumoricidal effects were compared in the high, moderate and low antigen expressing xenograft for SW1116, WiDr and KB tumor‐bearing n...

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Detalles Bibliográficos
Autores principales:	Kitamura, Kazuya, Takahashi, Toshio, Miyagaki, Takuya, Yamaoka, Nobuki, Tsurumi, Hiroshi, Ohtsuji, Eigo, Kamiguchi, Michiko, Noguchi, Akinori, Yamaguchi, Toshiharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1992
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918930/ https://www.ncbi.nlm.nih.gov/pubmed/1387634 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01978.x

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