Alteration of Type II Regulatory Subunit of cAMP‐dependent Protein Kinase in Human Cisplatin‐resistant Cells as a Basis of Collateral Sensitivity to 8‐Chloro‐cAMP

A cyclic adenosine 3′,5′‐monophosphate (cAMP) analogue, 8‐chloro‐cAMP (8‐Cl‐cAMP), had a collateral growth‐inhibitory effect on a cis‐diamminedichloroplatinum(II) (CDDP)‐resistant human cancer cell lines (PC‐14/CDDP). The non‐selective analogues dibutyryl‐cAMP, 8‐bromo‐cAMP and forskolin, which are...

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Detalles Bibliográficos
Autores principales: Nishio, Kazuto, Morikage, Toshihiko, Kubota, Naohiro, Ohmori, Tohru, Takeda, Yuichiro, Fujiwara, Yasuhiro, Miki, Keizaburo, Abe, Kaoru, Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918934/
https://www.ncbi.nlm.nih.gov/pubmed/1325432
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01976.x

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