CD7 Expression in Malignant Pleural Mesothelioma

CD7 antigen was found to be expressed on malignant mesothelioma arising from the right pleura in a 15‐year‐old girl not only by immunostaining using monoclonal antibodies, but also by Northern blot analysis. The level of expression in this tumor was comparable to those in T‐cell lines, Jurkat and CC...

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Autores principales: Hibi, Shigeyoshi, Kataoka, Yoshiko, Fujita, Naohisa, Okabe, Hidetoshi, Yoshikawa, Kazuhiro, Seto, Masao, Ueda, Ryuzo, Imashuku, Shinsaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918937/
https://www.ncbi.nlm.nih.gov/pubmed/1381341
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01965.x
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author Hibi, Shigeyoshi
Kataoka, Yoshiko
Fujita, Naohisa
Okabe, Hidetoshi
Yoshikawa, Kazuhiro
Seto, Masao
Ueda, Ryuzo
Imashuku, Shinsaku
author_facet Hibi, Shigeyoshi
Kataoka, Yoshiko
Fujita, Naohisa
Okabe, Hidetoshi
Yoshikawa, Kazuhiro
Seto, Masao
Ueda, Ryuzo
Imashuku, Shinsaku
author_sort Hibi, Shigeyoshi
collection PubMed
description CD7 antigen was found to be expressed on malignant mesothelioma arising from the right pleura in a 15‐year‐old girl not only by immunostaining using monoclonal antibodies, but also by Northern blot analysis. The level of expression in this tumor was comparable to those in T‐cell lines, Jurkat and CCRF‐CEM. Cytogenetic analysis of the tumor showed hypodiploidy (n = 43). CD7 has been regarded as one of the hematopoietic cell markers selectively expressed on the majority of T cells and multipotential stem cells. To our knowledge, this is the first report of a non‐hematopoietic tumor expressing CD7.
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spelling pubmed-59189372018-05-11 CD7 Expression in Malignant Pleural Mesothelioma Hibi, Shigeyoshi Kataoka, Yoshiko Fujita, Naohisa Okabe, Hidetoshi Yoshikawa, Kazuhiro Seto, Masao Ueda, Ryuzo Imashuku, Shinsaku Jpn J Cancer Res Rapid Communication CD7 antigen was found to be expressed on malignant mesothelioma arising from the right pleura in a 15‐year‐old girl not only by immunostaining using monoclonal antibodies, but also by Northern blot analysis. The level of expression in this tumor was comparable to those in T‐cell lines, Jurkat and CCRF‐CEM. Cytogenetic analysis of the tumor showed hypodiploidy (n = 43). CD7 has been regarded as one of the hematopoietic cell markers selectively expressed on the majority of T cells and multipotential stem cells. To our knowledge, this is the first report of a non‐hematopoietic tumor expressing CD7. Blackwell Publishing Ltd 1992-07 /pmc/articles/PMC5918937/ /pubmed/1381341 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01965.x Text en
spellingShingle Rapid Communication
Hibi, Shigeyoshi
Kataoka, Yoshiko
Fujita, Naohisa
Okabe, Hidetoshi
Yoshikawa, Kazuhiro
Seto, Masao
Ueda, Ryuzo
Imashuku, Shinsaku
CD7 Expression in Malignant Pleural Mesothelioma
title CD7 Expression in Malignant Pleural Mesothelioma
title_full CD7 Expression in Malignant Pleural Mesothelioma
title_fullStr CD7 Expression in Malignant Pleural Mesothelioma
title_full_unstemmed CD7 Expression in Malignant Pleural Mesothelioma
title_short CD7 Expression in Malignant Pleural Mesothelioma
title_sort cd7 expression in malignant pleural mesothelioma
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918937/
https://www.ncbi.nlm.nih.gov/pubmed/1381341
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01965.x
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