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Modifying Effects of Various Chemicals on Tumor Development in a Rat Wide‐spectrum Organ Carcinogenesis Model
The efficacy of a wide‐spectrum organ carcinogenesis model for detection of modification potential of exogenous agents was investigated in F344 male rats. Groups of animals were sequentially injected with N‐bis(2‐hydroxypropyl)nitrosamine (1000 mg/kg body weight, i.p., in saline, twice in week 1), N...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1992
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918946/ https://www.ncbi.nlm.nih.gov/pubmed/1399818 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01985.x |