DNA topoisomerase IIβ stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression

BACKGROUND: DNA topoisomerase IIβ (topo IIβ) is known to regulate neural differentiation by inducing the neuronal genes responsible for critical neural differentiation events such as neurite outgrowth and axon guidance. However, the pathways of axon growth controlled by topo IIβ have not been clarif...

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Detalles Bibliográficos
Autores principales: Zaim, Merve, Isik, Sevim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918966/
https://www.ncbi.nlm.nih.gov/pubmed/29695291
http://dx.doi.org/10.1186/s13287-018-0859-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918966/
https://www.ncbi.nlm.nih.gov/pubmed/29695291
http://dx.doi.org/10.1186/s13287-018-0859-4

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