Characterization of recent and minimally passaged Brazilian dengue viruses inducing robust infection in rhesus macaques

The macaque is widely accepted as a suitable model for preclinical characterization of dengue vaccine candidates. However, the only vaccine for which both preclinical and clinical efficacy results were reported so far showed efficacy levels that were substantially different between macaques and huma...

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Detalles Bibliográficos
Autores principales: Borges, Maria Beatriz, Marchevsky, Renato Sergio, Mendes, Ygara S., Mendes, Luiz Gustavo, Duarte, Ana Claudia, Cruz, Michael, de Filippis, Ana Maria Bispo, Vasconcelos, Pedro Fernando C., Freire, Marcos, Homma, Akira, Mossman, Sally, Lepine, Edith, Vanloubbeeck, Yannick, Lorin, Clarisse, Malice, Marie-Pierre, Caride, Elena, Warter, Lucile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919018/
https://www.ncbi.nlm.nih.gov/pubmed/29694440
http://dx.doi.org/10.1371/journal.pone.0196311

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