The Mechanism of the Difference in Cellular Uptake of Platinum Derivatives in Non‐small Cell Lung Cancer Cell Line (PC‐14) and Its Cisplatin‐resistant Subline (PC‐14/CDDP)

A cisplatin‐resistant non‐small cell lung cancer cell line, PC‐14/CDDP, was established from PC‐14 by stepwise escalation of CDDP concentrations in vitro. PC‐14/CDDP cells were 11.4‐fold more resistant to CDDP compared with PC‐14 cells. This resistant cell line was cross‐resistant to platinum analog...

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Detalles Bibliográficos
Autores principales: Ohmori, Tohru, Morikage, Toshihiko, Sugimoto, Yoshikazu, Fujiwara, Yasuhiro, Kasahara, Kazuo, Nishio, Kazuto, Ohta, Sei, Sasaki, Yasutsuna, Takahashi, Terumi, Saijo, Nagahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919029/
https://www.ncbi.nlm.nih.gov/pubmed/8383649
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02788.x

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