Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis

INTRODUCTION: One of the characteristics of early osteoarthritis (OA) is the loss of fixed charged density (FCD) of glycosaminoglycans in the superficial zone of articular cartilage. However, possible local changes in the FCD content of the pericellular matrix (PCM) are not fully understood. Hence,...

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Detalles Bibliográficos
Autores principales: Ojanen, Simo P., Finnilä, Mikko A. J., Reunamo, Aino E., Ronkainen, Ari P., Mikkonen, Santtu, Herzog, Walter, Saarakkala, Simo, Korhonen, Rami K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919041/
https://www.ncbi.nlm.nih.gov/pubmed/29694389
http://dx.doi.org/10.1371/journal.pone.0196203

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