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Multidrug Resistance in Rat Colon Carcinoma Cell Lines CC531, CC531(mdr+) and CC531(rev)

A rat colon carcinoma cell line, CC531, was exposed to stepwise increasing concentrations of colchicine. A cell line, CC531(mdr+), which grows in the presence of 0.2 μM of colchicine was obtained. A revertant cell line, CC531rev was isolated upon colchicine withdrawal. The CC531(mdr+) displayed a mu...

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Detalles Bibliográficos
Autores principales: Gheuens, Eric, van der Heyden, Sylke, Elst, Hilde, Eggermont, Alexander, Van Oosterom, Allan, De Bruijn, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919088/
https://www.ncbi.nlm.nih.gov/pubmed/7903965
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02822.x