Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ

Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human r...

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Autores principales: Hasegawa, Kiminori, Ariyama, Takeshi, Inazawa, Johji, Mizuno, Kazuya, Ogimoto, Mami, Katagiri, Tatsuo, Yakura, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919108/
https://www.ncbi.nlm.nih.gov/pubmed/8294211
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02825.x
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author Hasegawa, Kiminori
Ariyama, Takeshi
Inazawa, Johji
Mizuno, Kazuya
Ogimoto, Mami
Katagiri, Tatsuo
Yakura, Hidetaka
author_facet Hasegawa, Kiminori
Ariyama, Takeshi
Inazawa, Johji
Mizuno, Kazuya
Ogimoto, Mami
Katagiri, Tatsuo
Yakura, Hidetaka
author_sort Hasegawa, Kiminori
collection PubMed
description Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24.
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spelling pubmed-59191082018-05-11 Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ Hasegawa, Kiminori Ariyama, Takeshi Inazawa, Johji Mizuno, Kazuya Ogimoto, Mami Katagiri, Tatsuo Yakura, Hidetaka Jpn J Cancer Res Rapid Communication Protein tyrosine phosphatase (PTP) negatively regulates the effect of protein tyrosine kinases and is implicated in the regulation of a variety of biological phenomena such as cell activation, differentiation and neoplastic transformation. To gain insight into the role of PTPs, we cloned the human receptor‐type FTP gene and assigned the chromosome harboring the gene for HPTPδ by using DNAs from human‐mouse hybrid cell lines and by fluorescence in situ hybridization. The results clearly demonstrated that HPTPδ gene maps to human chromosome 9p24. Blackwell Publishing Ltd 1993-12 /pmc/articles/PMC5919108/ /pubmed/8294211 http://dx.doi.org/10.1111/j.1349-7006.1993.tb02825.x Text en
spellingShingle Rapid Communication
Hasegawa, Kiminori
Ariyama, Takeshi
Inazawa, Johji
Mizuno, Kazuya
Ogimoto, Mami
Katagiri, Tatsuo
Yakura, Hidetaka
Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title_full Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title_fullStr Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title_full_unstemmed Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title_short Chromosomal Assignment of the Gene for Protein Tyrosine Phosphatase HPTPδ
title_sort chromosomal assignment of the gene for protein tyrosine phosphatase hptpδ
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919108/
https://www.ncbi.nlm.nih.gov/pubmed/8294211
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02825.x
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