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Influence of Aging on Multi‐organ Carcinogenesis in Rats Induced by N‐Methyl‐N‐nitrosourea

The effects of aging on the multi‐organ Carcinogenesis induced in rats by N‐methyl‐N‐nitrosourea (MNU), a direct carcinogen which does not need metabolic activation to exert carcinogenicity, were examined in male F344 rats. In the first experiment, rats at 6, 52, and 98 weeks of age were treated wit...

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Detalles Bibliográficos
Autores principales: Mizoguchi, Masae, Naito, Hatsumi, Kurata, Yasushi, Shibata, Masa‐Aki, Tsuda, Hiroyuki, Wild, Christopher P., Montesano, Ruggero, Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919123/
https://www.ncbi.nlm.nih.gov/pubmed/8463131
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02847.x

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