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Brefeldin A Blocks the Cytotoxicity of T Cell Receptor α/β and γ/δ Cytotoxic T Lymphocyte Clones Reacting against Human Autologous Cancer Cells

We studied the effector mechanism of T cell receptor (TCR) α/β‐ and γ/δ‐type cytotoxic T lymphocyte (CTL) clones that react with human autologous tumor cells. Treatment of tumor cells with a fungal antibacterial reagent, brefeldin A (BFA), resulted in the inhibition of cytotoxicity of an autologous...

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Detalles Bibliográficos
Autores principales:	Wada, Yoshimasa, Ikeda, Hideyuki, Ueda, Daisuke, Ohta, Masahiko, Takahashi, Shuji, Hirata, Koichi, Sato, Noriyuki, Kikuchi, Kokichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1993
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919263/ https://www.ncbi.nlm.nih.gov/pubmed/8407555 http://dx.doi.org/10.1111/j.1349-7006.1993.tb02065.x

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