Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications

Use of hepatocytes derived from induced pluripotent stem cells (i-Heps) is limited by their functional differences in comparison with primary cells. Extracellular niche factors likely play a critical role in bridging this gap. Using image-based characterization (high content analysis; HCA) of freshl...

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Detalles Bibliográficos
Autores principales: Ong, John, Serra, Maria Paola, Segal, Joe, Cujba, Ana-Maria, Ng, Soon Seng, Butler, Richard, Millar, Val, Hatch, Stephanie, Zimri, Salman, Koike, Hiroyuki, Chan, Karen, Bonham, Andrew, Walk, Michelle, Voss, Ty, Heaton, Nigel, Mitry, Ragai, Dhawan, Anil, Ebner, Daniel, Danovi, Davide, Nakauchi, Hiromitsu, Rashid, S. Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919292/
https://www.ncbi.nlm.nih.gov/pubmed/29478892
http://dx.doi.org/10.1016/j.stemcr.2018.01.025

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