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HOXB4 Promotes Hemogenic Endothelium Formation without Perturbing Endothelial Cell Development

Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells, in vitro, holds great promise for regenerative therapies. Primarily, this has been achieved in mouse cells by overexpression of the homeotic selector protein HOXB4. The exact cellular stage at which HOXB4 promotes hematopoiet...

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Detalles Bibliográficos
Autores principales:	Teichweyde, Nadine, Kasperidus, Lara, Carotta, Sebastian, Kouskoff, Valerie, Lacaud, Georges, Horn, Peter A., Heinrichs, Stefan, Klump, Hannes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919293/ https://www.ncbi.nlm.nih.gov/pubmed/29456178 http://dx.doi.org/10.1016/j.stemcr.2018.01.009

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