Cargando…

Lysosome Labilizers Potentiate the Antitumor Effects of Tumor Necrosis Factor‐α

Enhancement of in vitro cytotoxic activity of tumor necrosis factor‐α (TNF‐α) was observfed in combination with lysosome labilizers, particularly with urokinase‐type plasminogen activator (u‐PA), tissue‐type plasminogen activator (t‐PA) and lipoprotein lipase (LPL). The concentration of TNF‐α result...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masegi, Tsukio, Kato, Arata, Kitai, Kazuo, Fukuoka, Masami, Soma, Kazuhiko, Ichikawa, Yataro, Nakamura, Satoshi, Watanabe, Naoki, Niitsu, Yoshiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1993
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919297/ https://www.ncbi.nlm.nih.gov/pubmed/8514612 http://dx.doi.org/10.1111/j.1349-7006.1993.tb00157.x

Ejemplares similares

Characterization of a Novel Human Tumor Necrosis Factor‐α Mutant with Increased Cytotoxic Activity
por: Masegi, Tsukio, et al.
Publicado: (1995)

Enhancement of Lysosomal Enzyme Activity by Recombinant Human Tumor Necrosis Factor and Its Role in Tumor Cell Killing in vitro
por: Watanabe, Naoki, et al.
Publicado: (1992)

Enhanced Antitumor Effect of Recombinant Human Tumor Necrosis Factor in Combination with Recombinant Human Granulocyte Colony‐stimulating Factor in BALB/c Mice
por: Maeda, Masahiro, et al.
Publicado: (1993)

Enhancement of Blood Stasis and Vascular Permeability in Meth‐A Tumors by Administration of Hyperthermia in Combination with Tumor Necrosis Factor
por: Umeno, Hiroshi, et al.
Publicado: (1994)

Induction of Synthesis of Heat Shock Protein 72 in Tumor Necrosis Factor Gene‐transduced Cells
por: Watanabe, Naoki, et al.
Publicado: (1994)

Mechanism of Synergistic Cytotoxic Effect between Tumor Necrosis Factor and Hyperthermia
por: Yamauchi, Naofumi, et al.
Publicado: (1992)

Reversal of Tumor Necrosis Factor Resistance in Tumor Cells by Adriamycin via Suppression of Intracellular Resistance Factors
por: Watanabe, Naoki, et al.
Publicado: (1995)

Augmented Systemic Immunity in Mice Implanted with Tumor Necrosis Factor‐α Gene‐transduced Meth‐A Cells
por: Fujii, Shigeyuki, et al.
Publicado: (1994)

Human Tumor–infiltrating Lymphocytes Transfected with Tumor Necrosis Factor Gene Could Augment Cytotoxicity to Autologous Tumor Cells
por: Itoh, Yoshinori, et al.
Publicado: (1991)

The role of lysosome in regulated necrosis
por: Alu, Aqu, et al.
Publicado: (2020)

A superior drug carrier – aponeocarzinostatin in partially unfolded state fully protects the labile antitumor enediyne
por: Shanmuganathan, Aranganathan, et al.
Publicado: (2009)

Close Correlation between the Dephosphorylation of p53 and Growth Suppression by Transforming Growth Factor‐β1 in Nasopharyngeal Carcinoma Cells Transduced with Adenovirus Early Region Genes
por: Mogi, Yoshihiro, et al.
Publicado: (1994)

Complete lysosomal disruption: A route to necrosis, not to the inflammasome
por: Guicciardi, Maria Eugenia, et al.
Publicado: (2013)

Platelet Aggregation Induced by Adenosine Diphosphate Released from Cloned Murine Fibrosarcoma Cells Is Positively Correlated with the Experimental Metastatic Potential of the Cells
por: Mogi, Yoshihiro, et al.
Publicado: (1991)

Alkali-labile gangliosides
por: Mauri, Laura, et al.
Publicado: (2023)

MSFragger-Labile: A Flexible Method to Improve Labile PTM Analysis in Proteomics
por: Polasky, Daniel A., et al.
Publicado: (2023)

Ventricular Repolarization Lability in Children With Kawasaki Disease
por: Kuriki, Marina, et al.
Publicado: (2011)

Enhanced Expression of Type IV Collagen‐binding Protein (p29) in Fyn‐transfected Murine Fibrosarcoma Cells
por: Koike, Kazuhiko, et al.
Publicado: (2002)

Linking Labile Heme with Thrombosis
por: Hopp, Marie-Thérèse, et al.
Publicado: (2021)

In vivo Antitumor Mechanism of Natural Human Tumor Necrosis Factor Involving a T Cell‐mediated Immunological Route
por: Asami, Tetsuya, et al.
Publicado: (1989)

Intracellular Metabolism and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugates of Differing Molar Ratios
por: Sasaki, Katsunori, et al.
Publicado: (1993)

Current and new antitumor necrosis factor agents in perspective
por: Maini, Ravinder N
Publicado: (2004)

The Functional Benefits of Preserving the Proximal Lower Leg Even in Total Necrosis of the Lower-Leg Muscles
por: Tsuge, Itaru, et al.
Publicado: (2020)

A Man with Labile Blood Pressure
por: Ma, Ronald C. W, et al.
Publicado: (2007)

Labile Exoten sollen physikrätsel lösen
Publicado: (1997)

Nature and Lability of Northern Adriatic Macroaggregates
por: Faganeli, Jadran, et al.
Publicado: (2010)

Koilocytes are enriched for alkaline-labile sites
por: Cortés-Gutiérrez, E.I., et al.
Publicado: (2010)

Glutathione and the intracellular labile heme pool
por: O’Keeffe, Rosemary, et al.
Publicado: (2020)

Modulation of lactate-lysosome axis in dendritic cells by clotrimazole potentiates antitumor immunity
por: Wang, Zining, et al.
Publicado: (2021)

Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis
por: Champa, Devora, et al.
Publicado: (2016)

Biosimilars to Antitumor Necrosis Factor Agents in Inflammatory Bowel Disease
por: Al Sulais, Eman, et al.
Publicado: (2020)

Enhancement of in vivo Antitumor Activity of a Novel Antimitotic 1‐Phenylpropenone Derivative, AM‐132, by Tumor Necrosis Factor‐cc or Interleukin‐6
por: Tatsumi, Yasuaki, et al.
Publicado: (2001)

Build-up of labile, non-labile carbon fractions under fourteen-year-old bamboo plantations in the Himalayan foothills
por: Kaushal, Rajesh, et al.
Publicado: (2021)

Synergistic Suppressive Effect of Double Transfection of Tumor Necrosis Factor‐α and Interleukin 12 Genes on Tumorigenicity of Meth‐A Cells
por: Fujiwara, Hitoshi, et al.
Publicado: (2000)

Harnessing the lysosome-dependent antitumor activity of phenothiazines in human small cell lung cancer
por: Zong, D, et al.
Publicado: (2014)

Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment
por: Hwang, Hui-Yun, et al.
Publicado: (2020)

Augmented Expression of a Type IV Collagen‐binding Protein in a Highly Metastatic Murine Fibrosarcoma Clone
por: Kogawa, Katsuhisa, et al.
Publicado: (1993)

Lability of the prolonged depolarizing afterpotential in Balanus photoreceptors
Publicado: (1977)

Lability of IgE Levels Early in Life
por: N'guessan, Koffi, et al.
Publicado: (2011)

Characterization of plasma labile heme in hemolytic conditions
por: Gouveia, Zélia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_2tu9qdkhs61e2l4115mg0khn6j