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Variation in K‐ras Codon 12 Point Mutation Rate with Histological Atypia within Individual Colorectal Tumors
To elucidate genetic alteration in relation to morphology and also to confirm more directly the proposed adenoma‐carcinoma sequence, we analyzed thirty‐eight colorectal “cancer in adenoma” lesions exhibiting areas of different atypia, in terms of K‐ras codon 12 point mutation. The mutation incidence...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1993
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919312/ https://www.ncbi.nlm.nih.gov/pubmed/8514605 http://dx.doi.org/10.1111/j.1349-7006.1993.tb00148.x |