Deletion of WT1 and WIT1 Genes and Loss of Heterozygosity on Chromosome 11p in Wilms Tumors in Japan

Six of 39 sporadic Wilms tumors had gross homozygous or hemizygous WT1 and WIT1 deletions. Two Wilms tumor‐aniridia‐genitourinary abnormalities‐mental retardation syndrome patients had total hemizygous WT1 and WIT1 deletions in both constitutional and nonsporadic type tumor cells. Four of the 8 tumo...

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Detalles Bibliográficos
Autores principales: Kaneko, Yasuhiko, Takeda, Osamu, Homma, Chieko, Maseki, Nobuo, Miyoshi, Hiroyuki, Tsunematsu, Yukiko, Williams, Bryan G., Saunders, Grady F., Sakurai, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919323/
https://www.ncbi.nlm.nih.gov/pubmed/8393432
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02021.x

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