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Long‐Evans A and C Rat Strains Susceptible to Clastogenic Effects of Chemicals in the Bone Marrow Cells

The Clastogenic responses to direct‐ and indirect‐acting carcinogens in bone marrow cells of LEA, LEC, Wistar and SD rats were compared. The frequency of chromosome aberrations (CA) induced by n‐butyl‐N‐nitrosourea or methylmethanesulfonate (MMS), which does not need metabolic activation, was signif...

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Detalles Bibliográficos
Autores principales: Ito, Yoshiaki, Fujie, Kimiko, Matsuda, Shuichi, Takahashi, Rei, Maeda, Sakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919336/
https://www.ncbi.nlm.nih.gov/pubmed/8106289
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02882.x