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5′‐Deoxy‐S‐fluorouridine Increases Daunorubicin Uptake in Multidrug‐resistant Cells and Its Activity Is Related with P‐gp 170 Expression

Most anticancer agents fail to induce clear responses in the treatment of colorectal cancer. This can be explained by involvement of overexpression of the membrane glycoprotein, P‐gp 170, which is associated with multidrug resistance (MDR), and/or with involvement of ras. Fluoropyrimidines are among...

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Detalles Bibliográficos
Autores principales:	van der Heyden, Sylke, Gheuens, Eric, van de Vrie, Wim, Van Bockstaele, Dirk, Van Oosterom, Allan, Eggermont, Alexander, De Bruijn, Ernst A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1994
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919339/ https://www.ncbi.nlm.nih.gov/pubmed/7906263 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02880.x

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