Alteration of the p53 Tumor Suppressor Gene Occurs Independently of K‐ras Activation and More Frequently in Serous Adenocarcinomas than in Other Common Epithelial Tumors of the Human Ovary

To clarify the role of the p53 tumor suppressor gene in the development of human ovarian epithelial tumors and to study the association of p53 alterations with K‐ras activation, a series of 70 common epithelial ovarian tumors from Japanese patients was studied. These included 31 serous adenocarcinom...

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Detalles Bibliográficos
Autores principales: Fujita, Masami, Enomoto, Takayuki, Inoue, Masaki, Tanizawa, Osamu, Ozaki, Masami, Rice, Jerry M., Nomura, Taisei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919385/
https://www.ncbi.nlm.nih.gov/pubmed/7852189
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02937.x

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