Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) remains a grave threat to world health with emerging drug resistant strains. One prominent feature of Mtb infection is the extensive reprogramming of host tissue at the site of infection. Here we report that inhibition of matrix metalloproteinase (MMP) activity by a...

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Detalles Bibliográficos
Autores principales: Xu, Yitian, Wang, Lihua, Zimmerman, Matthew D., Chen, Kai-Yuan, Huang, Lu, Fu, Dah-Jiun, Kaya, Firat, Rakhilin, Nikolai, Nazarova, Evgeniya V., Bu, Pengcheng, Dartois, Veronique, Russell, David G., Shen, Xiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919409/
https://www.ncbi.nlm.nih.gov/pubmed/29698476
http://dx.doi.org/10.1371/journal.ppat.1006974

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