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Megakaryocyte lineage development is controlled by modulation of protein acetylation
Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein acetylation affects normal myeloid development, and specifically megakaryocyte development. In the cur...
Autores principales: | Bartels, Marije, Govers, Anita, Polak, Roel, Vervoort, Stephin, van Boxtel, Ruben, Pals, Cornelieke, Bierings, Marc, van Solinge, Wouter, Egberts, Toine, Nieuwenhuis, Edward, Mokry, Michal, Coffer, Paul James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919413/ https://www.ncbi.nlm.nih.gov/pubmed/29698469 http://dx.doi.org/10.1371/journal.pone.0196400 |
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