Lower Incidence of K‐ras Codon 12 Mutation in Flat Colorectal Adenomas than in Polypoid Adenomas

In order to clarify genetic changes in flat adenomas, K‐ras codon 12 point mutations were examined in 56 flat adenomas, 81 polypoid adenomas and 42 cancers of colon and rectum. The mutation frequency in flat adenomas was 23% (13/56), significantly lower than that in polypoid adenomas (67%: 54/81) an...

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Detalles Bibliográficos
Autores principales: Yamagata, Seiichi, Muto, Tetsuichiro, Uchida, Yoshihiro, Masaki, Tadahiko, Sawada, Toshio, Tsuno, Nelson, Hirooka, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919417/
https://www.ncbi.nlm.nih.gov/pubmed/8144396
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02075.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919417/
https://www.ncbi.nlm.nih.gov/pubmed/8144396
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02075.x

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