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Lower Incidence of K‐ras Codon 12 Mutation in Flat Colorectal Adenomas than in Polypoid Adenomas
In order to clarify genetic changes in flat adenomas, K‐ras codon 12 point mutations were examined in 56 flat adenomas, 81 polypoid adenomas and 42 cancers of colon and rectum. The mutation frequency in flat adenomas was 23% (13/56), significantly lower than that in polypoid adenomas (67%: 54/81) an...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1994
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919417/ https://www.ncbi.nlm.nih.gov/pubmed/8144396 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02075.x |