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Detection of Guanine‐C8‐2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine Adduct as a Single Spot on Thin‐layer Chromatography by Modification of the (32)P‐Postlabeling Method
N‐(Deoxyguanosin‐8‐yl)‐2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (dG‐C8‐PhIP) has been shown to be a major adduct in DNA of rats given [(3)H]PhIP. However, when DNA from organs of rats fed PhIP was analyzed by the (32)P‐postlabeling method under standard and adduct‐intensification conditions,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919426/ https://www.ncbi.nlm.nih.gov/pubmed/8144391 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02068.x |