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Establishment and Characterization of Mouse‐Human Chimeric Monoclonal Antibody to erbB‐2 Product

A mouse‐human chimeric antibody for erbB‐2 product was established by a new procedure using heavy chain loss mouse mutant hybridoma and human immunoglobulin expression vector. The E401 hybridoma secreted anti‐erbB‐2 product monoclonal antibody (MoAb) (IgG1, k). The gene of the mouse variable regions...

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Detalles Bibliográficos
Autores principales: Ishida, Tadao, Tsujisaki, Masayuki, Hinoda, Yuji, Imai, Kohzoh, Yachi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919429/
https://www.ncbi.nlm.nih.gov/pubmed/7908285
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02079.x