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Biodistribution of Neocarzinostatin Conjugated to Chimeric Fab Fragments of the Monoclonal Antibody A7 in Nude Mice Bearing Human Pancreatic Cancer Xenografts

In this study, we conjugated chimeric Fab fragments of the monoclonal antibody (MAb) A7, which reacts with pancreatic cancers, to the antitumor drug neocarzinostatin (chA7Fab‐NCS) and intravenously injected (125)I‐labeled chA7Fab‐NCS into nude mice bearing a human pancreatic cancer xenograft. We com...

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Detalles Bibliográficos
Autores principales:	Otsuji, Eigo, Yamaguchi, Toshiharu, Yamaoka, Nobuki, Taniguchi, Katsunori, Kato, Makoto, Kotani, Tatsuya, Kitamura, Kazuya, Takahashi, Toshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1994
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919492/ https://www.ncbi.nlm.nih.gov/pubmed/8014111 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02391.x

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