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Circumvention of Daunorubicin Resistance by a New Tamoxifen Derivative, Toremifene, in Multidrug‐resistant Cell Line

The reversing effect of toremifene, a new tamoxifen derivative, on multidrug resistance in a K562 subline and its mechanism were studied. K562 cells were cultured in serially increasing concentrations up to 1.0 μM daunorubicin (DNR), and were found to be 28 times more resistant to DNR in comparison...

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Detalles Bibliográficos
Autores principales: Urasaki, Yoshimasa, Ueda, Takanori, Nakamura, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919521/
https://www.ncbi.nlm.nih.gov/pubmed/7914886
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02410.x

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