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Transfection‐induced Tumor Necrosis Factor‐α Increases the Susceptibility of Human Glioma Cells to Lysis by Lymphokine‐activated Killer Cells: Continuous Expression of Intercellular Adhesion Molecule‐1 on the Glioma Cells

To develop more effective adoptive immunotherapy, we transfected the human tumor necrosis factor‐α (TNF‐α) gene into human glioma cells (U251‐SP), which were used as target cells. TNF‐α is known to increase both the expression of intercellular adhesion molecule‐1 (ICAM‐1) on the surface of glioma ce...

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Detalles Bibliográficos
Autores principales: Takaoka, Toru, Yoshida, Jun, Mizuno, Masaaki, Sugita, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919548/
https://www.ncbi.nlm.nih.gov/pubmed/7915264
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02424.x