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Transfection‐induced Tumor Necrosis Factor‐α Increases the Susceptibility of Human Glioma Cells to Lysis by Lymphokine‐activated Killer Cells: Continuous Expression of Intercellular Adhesion Molecule‐1 on the Glioma Cells
To develop more effective adoptive immunotherapy, we transfected the human tumor necrosis factor‐α (TNF‐α) gene into human glioma cells (U251‐SP), which were used as target cells. TNF‐α is known to increase both the expression of intercellular adhesion molecule‐1 (ICAM‐1) on the surface of glioma ce...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1994
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919548/ https://www.ncbi.nlm.nih.gov/pubmed/7915264 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02424.x |