Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone

A new cancer cell line (Lu‐165) producing a large amount of anti‐diuretic hormone (ADH, 2.8 μg/g protein) was established from a 50‐year‐old small cell lung cancer patient presenting with a syndrome of inappropriate anti‐diuretic hormone secretion. These cells grew well in serum‐supplemented medium...

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Detalles Bibliográficos
Autores principales: Terasaki, Takeo, Matsuno, Yoshihiro, Shimosato, Yukio, Yamaguchi, Ken, Ichinose, Hiroshi, Nagatsu, Toshiharu, Kato, Kanefusa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1994
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919549/
https://www.ncbi.nlm.nih.gov/pubmed/8071114
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02420.x
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author Terasaki, Takeo
Matsuno, Yoshihiro
Shimosato, Yukio
Yamaguchi, Ken
Ichinose, Hiroshi
Nagatsu, Toshiharu
Kato, Kanefusa
author_facet Terasaki, Takeo
Matsuno, Yoshihiro
Shimosato, Yukio
Yamaguchi, Ken
Ichinose, Hiroshi
Nagatsu, Toshiharu
Kato, Kanefusa
author_sort Terasaki, Takeo
collection PubMed
description A new cancer cell line (Lu‐165) producing a large amount of anti‐diuretic hormone (ADH, 2.8 μg/g protein) was established from a 50‐year‐old small cell lung cancer patient presenting with a syndrome of inappropriate anti‐diuretic hormone secretion. These cells grew well in serum‐supplemented medium and during more than 100 passages they continued producing a large amount of this hormone. This cell line will be a useful tool for studies of the biochemistry and pathology of ADH‐producing cancer.
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spelling pubmed-59195492018-05-11 Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone Terasaki, Takeo Matsuno, Yoshihiro Shimosato, Yukio Yamaguchi, Ken Ichinose, Hiroshi Nagatsu, Toshiharu Kato, Kanefusa Jpn J Cancer Res Article A new cancer cell line (Lu‐165) producing a large amount of anti‐diuretic hormone (ADH, 2.8 μg/g protein) was established from a 50‐year‐old small cell lung cancer patient presenting with a syndrome of inappropriate anti‐diuretic hormone secretion. These cells grew well in serum‐supplemented medium and during more than 100 passages they continued producing a large amount of this hormone. This cell line will be a useful tool for studies of the biochemistry and pathology of ADH‐producing cancer. Blackwell Publishing Ltd 1994-07 /pmc/articles/PMC5919549/ /pubmed/8071114 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02420.x Text en
spellingShingle Article
Terasaki, Takeo
Matsuno, Yoshihiro
Shimosato, Yukio
Yamaguchi, Ken
Ichinose, Hiroshi
Nagatsu, Toshiharu
Kato, Kanefusa
Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title_full Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title_fullStr Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title_full_unstemmed Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title_short Establishment of a Human Small Cell Lung Cancer Cell Line Producing a Large Amount of Anti‐diuretic Hormone
title_sort establishment of a human small cell lung cancer cell line producing a large amount of anti‐diuretic hormone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919549/
https://www.ncbi.nlm.nih.gov/pubmed/8071114
http://dx.doi.org/10.1111/j.1349-7006.1994.tb02420.x
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