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Synergistic Enhancement of Cisplatin Cytotoxicity by SN‐38, an Active Metabolite of CPT‐11, for Cisplatin‐resistant HeLa Cells

A cisplatin (cis‐diamininedichloroplatinuin(II); CDDP)‐resistant HeLa cell line (HeLa/CDDP cells), which showed more than 8‐fold resistance to CDDF compared to the parent cells, was newly established for this study. HeLa/CDDP cells accumulated 50% less platinum than the parent cells. There was no di...

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Detalles Bibliográficos
Autores principales:	Minagawa, Yukihisa, Kigawa, Junzo, Ishihara, Hiroshi, Itamochi, Hiroaki, Terakawa, Naoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1994
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919584/ https://www.ncbi.nlm.nih.gov/pubmed/7961127 http://dx.doi.org/10.1111/j.1349-7006.1994.tb02976.x

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