Cargando…

Medroxyprogesterone acetate, unlike norethisterone, increases HIV-1 replication in human peripheral blood mononuclear cells and an indicator cell line, via mechanisms involving the glucocorticoid receptor, increased CD4/CD8 ratios and CCR5 levels

High usage of progestin-only injectable contraceptives, which include the intramuscular injectables depo-medroxyprogesterone acetate (DMPA-IM, Depo-Provera) and norethisterone (NET) enanthate (NET-EN or Nur-Isterate), correlates worldwide with areas of high HIV-1 prevalence. Epidemiological data sho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maritz, Michelle F., Ray, Roslyn M., Bick, Alexis J., Tomasicchio, Michele, Woodland, John G., Govender, Yashini, Avenant, Chanel, Hapgood, Janet P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919616/ https://www.ncbi.nlm.nih.gov/pubmed/29698514 http://dx.doi.org/10.1371/journal.pone.0196043

Ejemplares similares

The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
por: Ray, Roslyn M., et al.
Publicado: (2019)

The Injectable-Only Contraceptive Medroxyprogesterone Acetate, Unlike Norethisterone Acetate and Progesterone, Regulates Inflammatory Genes in Endocervical Cells via the Glucocorticoid Receptor
por: Govender, Yashini, et al.
Publicado: (2014)

The Progestin-Only Contraceptive Medroxyprogesterone Acetate, but Not Norethisterone Acetate, Enhances HIV-1 Vpr-Mediated Apoptosis in Human CD4(+) T Cells through the Glucocorticoid Receptor
por: Tomasicchio, Michele, et al.
Publicado: (2013)

Increased HIV‐1 infection in PBMCs treated in vitro with menstrual cycle phase hormones or medroxyprogesterone acetate likely occurs via different mechanisms
por: Bick, Alexis J., et al.
Publicado: (2022)

Counting the costs: Comparing depot medroxyprogesterone acetate and norethisterone oenanthate utilisation patterns in South Africa
por: Smit, Jennifer, et al.
Publicado: (2001)

Increased Cervical CD4(+)CCR5(+) T Cells Among Kenyan Sex Working Women Using Depot Medroxyprogesterone Acetate
por: Lajoie, Julie, et al.
Publicado: (2019)

The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis–Specific Host Immunity Through the Glucocorticoid Receptor
por: Tomasicchio, Michele, et al.
Publicado: (2019)

Is the Injectable Contraceptive Depo-Medroxyprogesterone Acetate (DMPA-IM) Associated with an Increased Risk for HIV Acquisition? The Jury Is Still Out
por: Hapgood, Janet P.
Publicado: (2020)

57 Increased Frequency of CD4+ CCR4+ CCR9+ Cells in Patients With Allergic Conjunctivitis
por: Alonso-Sánchez, Miguel E., et al.
Publicado: (2012)

Norethisterone‐induced cholestasis: A case report
por: Moussaoui, Safa, et al.
Publicado: (2022)

Norethisterone Enanthate Increases Mouse Susceptibility to Genital Infection with Herpes Simplex Virus Type 2 and HIV Type 1
por: Quispe Calla, Nirk E., et al.
Publicado: (2020)

Chemokine Receptors CCR1 and CCR2 on Peripheral Blood Mononuclear Cells of Newly Diagnosed Patients with the CD38-Positive Chronic Lymphocytic Leukemia
por: Kholodnyuk, Irina, et al.
Publicado: (2020)

Norethisterone enanthate-induced cerebral venous sinus thrombosis (CVST)
por: Bahall, Mandreker, et al.
Publicado: (2017)

Rare case of norethisterone‐induced hepatitis: A case report
por: Arafa, Eiman A., et al.
Publicado: (2022)

CCR5 Receptor Occupancy Analysis Reveals Increased Peripheral Blood CCR5+CD4+ T Cells Following Treatment With the Anti-CCR5 Antibody Leronlimab
por: Chang, Xiao L., et al.
Publicado: (2021)

Increased CCR7(lo)PD-1(hi)CXCR5(+)CD4(+) T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection
por: Huang, Ya-Xin, et al.
Publicado: (2018)

Increased frequency of CCR4+ and CCR6+ memory T-cells including CCR7+CD45RA(med )very early memory cells in granulomatosis with polyangiitis (Wegener's)
por: Fagin, Ursula, et al.
Publicado: (2012)

Dienogest versus norethisterone acetate in management of endometrial hyperplasia without atypia
por: Girbash, Ehab F., et al.
Publicado: (2023)

Norethisterone-Induced Liver Injury and a Short Survey Among Gynecologists
por: Rather, Jawad Iqbal, et al.
Publicado: (2023)

Intestinal endothelial cells increase HIV infection and latency in resting and activated CD4 + T cells, particularly affecting CCR6 + CD4 + T cells
por: Eddy, Jessica, et al.
Publicado: (2023)

Warming Arctic summers unlikely to increase productivity of shorebirds through renesting
por: Saalfeld, Sarah T., et al.
Publicado: (2021)

Grazing cattle, well-managed or not, is unlikely to increase soil carbon sequestration
por: Lajtha, Kate, et al.
Publicado: (2022)

Norethisterone Reduces Vaginal Bleeding Caused by Progesterone-Only Birth Control Pills
por: Vilk Ayalon, Naama, et al.
Publicado: (2022)

Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids
por: Syed, Yahiya Y.
Publicado: (2022)

Systemic DPP4/CD26 is associated with natural HIV-1 control: Implications for COVID-19 susceptibility
por: Govender, Yashini, et al.
Publicado: (2021)

Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients
por: Xu, Zhuwei, et al.
Publicado: (2009)

Chlamydia pneumoniae-Induced IFN-Gamma Responses in Peripheral Blood Mononuclear Cells Increase Numbers of CD4+ but Not CD8+ T Effector Memory Cells
por: Smith-Norowitz, Tamar A, et al.
Publicado: (2021)

CCR5 deficiency impairs CD4(+) T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis
por: Martín‐Leal, Ana, et al.
Publicado: (2020)

DRESS syndrome: an unlikely diagnosis with an unlikely cause
por: Soares, Sofia Garcês, et al.
Publicado: (2022)

CCR7 is required for the in vivo function of CD4(+) CD25(+) regulatory T cells
por: Schneider, Martin A., et al.
Publicado: (2007)

The Primodos components Norethisterone acetate and Ethinyl estradiol induce developmental abnormalities in zebrafish embryos
por: Brown, Samantha, et al.
Publicado: (2018)

Correction: Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids
por: Syed, Yahiya Y.
Publicado: (2022)

Medroxyprogesterone Acetate Alters Mycobacterium Bovis BCG-Induced Cytokine Production in Peripheral Blood Mononuclear Cells of Contraceptive Users
por: Kleynhans, Léanie, et al.
Publicado: (2011)

Humanized anti CCR4 antibody KW0761 targets HTLV-1 infected CD4+ CCR4+ and CD8+CCR4+ T cells to treat HAM/TSP
por: Yamano, Yoshihisa, et al.
Publicado: (2015)

Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes
por: Takeda, Yoshito, et al.
Publicado: (2003)

Unique Chemotactic Response Profile and Specific Expression of Chemokine Receptors Ccr4 and Ccr8 by Cd4(+)Cd25(+) Regulatory T Cells
por: Iellem, Andrea, et al.
Publicado: (2001)

Stage-Dependent Increase of Systemic Immune Activation and CCR5(+)CD4(+) T Cells in Filarial Driven Lymphedema in Ghana and Tanzania
por: Rahamani, Abu Abudu, et al.
Publicado: (2023)

Expression of CCR8 is increased in asthma
por: Mutalithas, K, et al.
Publicado: (2010)

Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice
por: Wessels, Jocelyn M., et al.
Publicado: (2019)

Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice
por: Wessels, Jocelyn M., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_da997u164g7b95k3i4al6n0oho