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KSHV induces immunoglobulin rearrangements in mature B lymphocytes

Kaposi sarcoma herpesvirus (KSHV/HHV-8) is a B cell tropic human pathogen, which is present in vivo in monotypic immunoglobulin λ (Igλ) light chain but polyclonal B cells. In the current study, we use cell sorting to infect specific B cell lineages from human tonsil specimens in order to examine the...

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Detalles Bibliográficos
Autores principales:	Totonchy, Jennifer, Osborn, Jessica M., Chadburn, Amy, Nabiee, Ramina, Argueta, Lissenya, Mikita, Geoffrey, Cesarman, Ethel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919685/ https://www.ncbi.nlm.nih.gov/pubmed/29659614 http://dx.doi.org/10.1371/journal.ppat.1006967

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