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Upregulation of E-cadherin expression mediated by a novel dsRNA suppresses the growth and metastasis of bladder cancer cells by inhibiting β-catenin/TCF target genes

Low expression levels of E-cadherin are correlated with poor prognosis in patients with bladder cancer (BCa). A small activating RNA (saRNA) targeting a specific promoter region can activate gene expression. In the present study, two small double-stranded RNAs (dsRNAs) targeting the promoter region...

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Detalles Bibliográficos
Autores principales: Li, Chuanchang, Liu, Jiaxuan, Zhang, Qingsong, Cui, Kai, Ge, Qiangqiang, Wang, Chenghe, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919711/
https://www.ncbi.nlm.nih.gov/pubmed/29620261
http://dx.doi.org/10.3892/ijo.2018.4346