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Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling

Cushing's disease is primarily caused by pituitary adrenocorticotropin-secreting adenoma. However, its pathogenesis has remained obscure. In the present study, whole transcriptome analysis was performed by RNA sequencing (RNA-Seq) and expression of secreted frizzled-related protein 2 (SFRP2) wa...

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Detalles Bibliográficos
Autores principales:	Ren, Jie, Jian, Fangfang, Jiang, Hong, Sun, Yuhao, Pan, Sijian, Gu, Changwei, Chen, Xiao, Wang, Weiqing, Ning, Guang, Bian, Liuguan, Sun, Qingfang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919716/ https://www.ncbi.nlm.nih.gov/pubmed/29620167 http://dx.doi.org/10.3892/ijo.2018.4355

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