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S-phase kinase-associated protein 2 is involved in epithelial-mesenchymal transition in methotrexate-resistant osteosarcoma cells

Osteosarcoma (OS), a common worldwide primary aggressive bone malignancy, arises from primitive transformed cells of mesenchymal origin and usually attacks adolescents and young adults. Methotrexate (MTX) is the anti-folate drug used as a pivotal chemotherapeutic agent in the treatment of OS. Howeve...

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Detalles Bibliográficos
Autores principales:	Ding, Lu, Wang, Chengwei, Cui, Yong, Han, Xiaoping, Zhou, Yang, Bai, Jingping, Li, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919717/ https://www.ncbi.nlm.nih.gov/pubmed/29620168 http://dx.doi.org/10.3892/ijo.2018.4345

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