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Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies
Nonmodel rodents are widely used as subjects for both basic and applied biological research, but the genetic diversity of the study individuals is rarely quantified. University-housed colonies tend to be small and subject to founder effects and genetic drift; so they may be highly inbred or show sub...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919727/ https://www.ncbi.nlm.nih.gov/pubmed/29242387 http://dx.doi.org/10.1534/g3.117.300495 |