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Genetic Identification of Separase Regulators in Caenorhabditis elegans

Separase is a highly conserved protease required for chromosome segregation. Although observations that separase also regulates membrane trafficking events have been made, it is still not clear how separase achieves this function. Here, we present an extensive ENU mutagenesis suppressor screen aimed...

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Detalles Bibliográficos
Autores principales: Melesse, Michael, Sloan, Dillon E., Benthal, Joseph T., Caylor, Quincey, Gosine, Krishen, Bai, Xiaofei, Bembenek, Joshua N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919728/
https://www.ncbi.nlm.nih.gov/pubmed/29246899
http://dx.doi.org/10.1534/g3.117.300298