Bayesian Diallel Analysis Reveals Mx1-Dependent and Mx1-Independent Effects on Response to Influenza A Virus in Mice

Influenza A virus (IAV) is a respiratory pathogen that causes substantial morbidity and mortality during both seasonal and pandemic outbreaks. Infection outcomes in unexposed populations are affected by host genetics, but the host genetic architecture is not well understood. Here, we obtain a broad...

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Detalles Bibliográficos
Autores principales: Maurizio, Paul L., Ferris, Martin T., Keele, Gregory R., Miller, Darla R., Shaw, Ginger D., Whitmore, Alan C., West, Ande, Morrison, Clayton R., Noll, Kelsey E., Plante, Kenneth S., Cockrell, Adam S., Threadgill, David W., Pardo-Manuel de Villena, Fernando, Baric, Ralph S., Heise, Mark T., Valdar, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Multiparental Populations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919740/
https://www.ncbi.nlm.nih.gov/pubmed/29187420
http://dx.doi.org/10.1534/g3.117.300438

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