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A 12.3-kb Duplication Within the VWF Gene in Pigs Affected by Von Willebrand Disease Type 3
Von Willebrand Disease (VWD) type 3 is a serious and sometimes fatal hereditary bleeding disorder. In pigs, the disease has been known for decades, and affected animals are used as models for the human disease. Due to the recessive mode of inheritance of VWD type 3, severe bleeding is typically seen...
Autores principales: | Lehner, Stefanie, Ekhlasi-Hundrieser, Mahnaz, Detering, Carsten, Allerkamp, Hanna, Pfarrer, Christiane, von Depka Prondzinski, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919753/ https://www.ncbi.nlm.nih.gov/pubmed/29208651 http://dx.doi.org/10.1534/g3.117.300432 |
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