Sub-noxious Intravesical Lipopolysaccharide Triggers Bladder Inflammation and Symptom Onset in A Transgenic Autoimmune Cystitis Model: A MAPP Network Animal Study

Patients with interstitial cystitis/bladder pain syndrome (IC/BPS) can potentially develop symptom flares after exposure to minor bladder irritants such as subclinical bacterial infection. To reproduce this symptom onset, we intravesically instilled a sub-noxious dose of uropathogenic E. coli compon...

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Detalles Bibliográficos
Autores principales: Kogan, Paul, Xu, Suming, Wang, Yaoqin, O’Donnell, Michael A., Lutgendorf, Susan K., Bradley, Catherine S., Schrepf, Andrew, Kreder, Karl J., Luo, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919907/
https://www.ncbi.nlm.nih.gov/pubmed/29700406
http://dx.doi.org/10.1038/s41598-018-24833-x

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