Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates

Antibody–drug conjugates (ADCs) are attractive in cancer therapy because they can directly bind to cancer cells and provide anticancer activity. To kill cancer cells with ADCs, the target antigens are required not only to be highly and/or selectively expressed on cancer cells but also internalized b...

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Detalles Bibliográficos
Autores principales: Kikkawa, Yamato, Enomoto-Okawa, Yurie, Fujiyama, Aiko, Fukuhara, Takeshi, Harashima, Nozomi, Sugawara, Yumika, Negishi, Yoichi, Katagiri, Fumihiko, Hozumi, Kentaro, Nomizu, Motoyoshi, Ito, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919910/
https://www.ncbi.nlm.nih.gov/pubmed/29700410
http://dx.doi.org/10.1038/s41598-018-24961-4

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